https://pubs.rsc.org/en/content/articlelanding/2016/ob/c5ob01892g
Replacements for Toxic Solvents
Solvent |
Possible alternatives |
CH2Cl2 (52) |
1,4-Dioxane (6) |
Dimethyl carbonate (56) |
|
4-Methyltetrahydropyran (30) |
|
CHCl3 (47) |
Fluorobenzene (75) |
Trifluorotoluene (39) |
|
Cl(CH2)2Cl (2) |
Fluorobenzene (75) |
Trifluorotoluene (39) |
|
CCl4 (45) |
Trifluorotoluene (39) |
Decalin (48) |
|
p-Xylene (121) |
|
Benzene (37) |
m-Xylene (103) |
o-Xylene (114) |
|
Toluene (131) |
|
Fluorobenzene (75) |
|
Dipropylene glycol dimethyl ether (63) |
|
DMSO (58) |
1-Methylimidazole (9) |
4-Formylmorpholine (28) |
|
N-Methylpyrrolidinone (112) |
|
1,3-Dimethylimidazolidin-2-one (4) |
|
Ethylene carbonate (72) |
|
DMF (106) |
N,N-Dimethylacetamide (105) |
Pyridine (122) |
|
Tetramethylurea (1) |
|
N-Methylpyrrolidinone (112) |
|
1-Methylimidazole (9) |
|
HMPA (85) |
DMPU (104) |
1-Ethyl-2-pyrrolidinone (8) |
|
1,3-Dimethylimidazolidin2-one (4) |
|
N-Methylpyrrolidinone (112) |
|
Quinoline (124) |
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